A category of drugs that have less potential for abuse or addiction than Schedule II or I drugs. Among the substances so classified by the Drug Enforcement Agency are glutethimide and various analgesic compounds containing codeine. Any drug or therapeutic agent–commonly understood to include narcotics, with a potential for abuse or addiction, which is held under strict governmental control, as delineated by the Comprehensive Drug Abuse Prevention & Control Act passed in 1970 Schedule I drugs High abuse potential, no accepted medical use in US–Acetorphine, acetyl methadol, allyprodine, α—acetylmethadol, bufotenine, dextromoramide, diethyltryptamine, dimethyltryptamine–DMT, etorphine, heroin, ibogaine, ketobemidone, LSD–N, N-diethyl-D-lysergamide or lysergic acid diethylamide, marijuana, mescaline, PCP–phencyclidine, peyote, phenadoxone, phenampromide, racomoramide, tetrahydrocannibol Schedule II High abuse potential, potentially leading to severe psychologic or physical dependence; schedule II agents have acceptable medical uses, eg narcotics–alphaprodine, anileridine, cocaine, codeine, diphenoxylate, diprenorphine, etorphine HCl, ethymorphine, hydrocordone, hydromorphone, levorphanol, meperidine, methadone, morphine, oxymorphone, poppy straw concentrates, powdered opium, raw opium, thebaine and non-narcotics–amphetamine, amobarbital, methaqualone, methamphetamine, methaqualone, pentobarbital, percodan, phencyclidine, phenmetrazine, secobarbital Schedule III High abuse potential, moderate to low physical dependence, and high psychologic dependence potential, with acceptable medical uses, which may be narcotic–eg nalorphine, paregoric, or nonnarcotic–eg aprobarbital, benzphentamine, butabarbital, chlorphentermine, chlortermine, glutethimide, mazindol, methyprylon, phendimetrazine, probarbital, talbutal, thiamylal, thiopental, vinbarbital Schedule IV Minimal abuse potential, limited physical or psychological dependence potential, nonnarcotic, eg barbital, chloral hydrate, chlordiazepoxide, clonazepam, chlorazepate, dextropropoxyphene, diazepam, diethylpropion, ethchlorvynol, ethinamate, fenfluramine, lorazepam, mebutamate, methobarbital, meprobamate, methohexital, oxazepam, paraldehyde, phenobarbital, phentermine, prazepam Schedule V Very low abuse/dependence potential–eg brown mixture–opium, some codeine preparations, diphenozylate preparations–Lomotil, ethylmorphine-Cidicol, opium–Donnagel-PG, terpin hydrate, or non-narcotic, eg loperamide approved under the FDA's Subpart H regulations governing distribution, Orphan Medical has developed a system that makes Xyrem available to patients exclusively from a single source -- the SDS specialty pharmacy. with a few exceptions including Department of Corrections and licensed hospice facilities, in connection with specified surgical procedures in certain timeframes, in approved clinical trials and complimentary or sample controlled substances. 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