Antidepressants are the most commonly prescribed medication for adults ages 18 to 44 years. In addition to depression, antidepressants treat a number of other conditions, including anxiety, panic disorder and obsessive-compulsive disorder, or OCD. Sertraline hydrochloride (Zoloft) is an antidepressant that belongs to a class called selective serotonin reuptake inhibitors, or SSRIs. Studies have shown sertraline to be effective for treating major depressive disorder, panic disorder, OCD, post-traumatic stress disorder and social anxiety disorder. Like other SSRIs, sertraline can have a variety of side effects. Symptoms may also occur if a person abruptly stops taking sertraline. Sertraline hydrochloride causes side effects in a variety of body systems -- most commonly nausea, sleep disturbance, sexual dysfunction, headache, appetite changes and dry mouth. The SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial was a randomized, double-blind, placebo-controlled trial of sertraline 50 to 200 mg/day versus matching placebo for 12 weeks. All participants also received nurse-facilitated support. Eligible patients were age 45 years or older with HF (left ventricular ejection fraction ≤45%, New York Heart Association functional class II to IV) and clinical depression (Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition criteria for current major depressive disorder). Those with significant cognitive impairment, psychosis, recent alcohol or drug dependence, bipolar or severe personality disorder, active suicidal ideation, and current antipsychotic or antidepressant medications were excluded. Primary end points were change in depression severity (Hamilton Depression Rating Scale total score) and composite cardiovascular status at 12 weeks. A total of 469 patients were randomized (n = 234 sertraline, n = 235 placebo). The mean ± SE change from baseline to 12 weeks in the Hamilton Depression Rating Scale total score was −7.1 ± 0.5 (sertraline) and −6.8 ± 0.5 (placebo) (p Sertraline was safe in patients with significant HF. However, treatment with sertraline compared with placebo did not provide greater reduction in depression or improved cardiovascular status among patients with HF and depression. Zoloft blood thinner Cialis cream Valacyclovir dosage for herpes zoster Metformin to conceive Aug 24, 2010. The objective was to test the hypothesis that heart failure HF patients treated with sertraline will have lower depression scores and fewer. Zoloft Sertraline is an antidepressant primarily used to treat major. are blood thinners like warfarin Coumadin, Jantoven and heart-rhythm. Zoloft sertraline is an SSRI selective serotonin reuptake inhibitors. cough and cold medicines, other antidepressants, heart rhythm medications, or migraine. In people with heart disease, depression is more likely to lead to heart attack, stroke and chest pain than is smoking, high blood pressure or even diabetes. But the odds can be evened by taking antidepressants known as selective serotonin reuptake inhibitors (SSRIs), according to a Canadian study published in the 2007 Patients who suffer depression--around 50% of those hospitalized and as many as one-fifth of others--are up to five times more likely to die or experience further heart problems within the next year than others. SSRIs, such as Celexa (citalopram), Prozac (fluoxetine) and Zoloft (sertraline), are thought to improve mood by preventing nerve cells from reabsorbing serotonin, thus increasing the amount of the neurotransmitter in the brain. Having low levels of serotonin is associated with depression, so "reuptake inhibitors," by keeping more serotonin available to the brain, may relieve depression. These medications are safe for heart patients and work well for many. During the first few weeks of taking an SSRI, patients may actually experience increased anxiety until the drug is fully effective -- usually in 4 to 6 weeks. Adverse effects that may last throughout the time the medication is taken include sexual difficulties, nausea, and headache. Zoloft (sertraline) belongs to a class of medications called selective serotonin reuptake inhibitors, or SSRIs. These medications work by increasing the level of serotonin in the brain. Low levels of serotonin in the brain are linked to a depressed mood in addition to cognitive difficulties like poor memory. It's important that you don't expect immediate results when taking Zoloft. People typically notice some improvement within a week or two, but it may take several weeks until you feel the full effects of the drug. Also, when you start taking Zoloft, you may experience some side effects. The most common ones include nausea or upset stomach, diarrhea, sweating, tremor, or a decreased appetite. Sertraline heart What to Keep in Mind If Your Doctor Prescribes Zoloft - Verywell Mind, Zoloft Sertraline - Side Effects, Dosage, Interactions - Drugs Clonidine for opiate addictionDoes clonidine cause bradycardiaValtrex not workingPrednisone side effects diarrheaViagra depression Jun 22, 2003. PATIENTS are beginning to treat depression with respect. Whether their doctors are ready to do so is less clear. A study in the current issue of. The Nation Side Effects; Your Zoloft Might Prevent a Heart Attack.. Common Side Effects of Zoloft Sertraline Hcl Drug Center - RxList. Antidepressant Use Among People With Heart Disease. Jan 31, 2013. "Heart risk link to SSRI antidepressants confirmed," BBC News reports. The BBC goes on to say that "some but not all antidepressant drugs. Aug 7, 2016. Official video for 'Change of Heart' by Sertraline 'Change of Heart' is available to download NOW via iTunes Soon to be available on Amazon. He has New York Heart Association class 3 heart failure with a left. treatment in patients with heart failure and depression.12 In that 12-week trial, sertraline.