Sertraline is indicated for the treatment of: Major depressive episodes. Prevention of recurrence of major depressive episodes. Obsessive compulsive disorder (OCD) in adults and paediatric patients aged 6-17 years. Post traumatic stress disorder (PTSD) Depression and OCD Sertraline treatment should be started at a dose of 50 mg/day. Panic Disorder, PTSD, and Social Anxiety Disorder Therapy should be initiated at 25 mg/day. After one week, the dose should be increased to 50 mg once daily. This dosage regimen has been shown to reduce the frequency of early treatment emergent side effects characteristic of panic disorder. Depression, OCD, Panic Disorder, Social Anxiety Disorder and PTSD Patients not responding to a 50 mg dose may benefit from dose increases. Dose changes should be made in steps of 50 mg at intervals of at least one week, up to a maximum of 200 mg/day. The FDA has approved sertraline for the treatment of depression, obsessive compulsive disorder (OCD), post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social anxiety disorder (SAD). Sertraline is also used for a number of other problems, such as: Sertraline has been approved to treat severe OCD in children between the ages of 6 and 17. Therapy is usually started at 50 mg/day and the dose is increased at weekly intervals if necessary. Children and older people often need smaller doses of medication and may start with 25 mg/day. People with liver disease may need a smaller dose of sertraline. We don't know exactly what causes depression and other mental health problems, but one theory that is pretty well-accepted is that there is chemical imbalance in the brain and nervous tissue. Several chemicals called neurotransmitters help nerve cells communicate, and serotonin is one of those chemicals. Nerve impulses cause the cell to release serotonin. The serotonin travels across the gap between cells and attaches to the other cell. Sertraline is a serotonin selective reuptake inhibitor; it keeps serotonin from being reabsorbed and allows it to accumulate, restoring chemical balance. Prednisone diarrhea Buy proscar for hair loss Do you need a prescription to buy retin a in canada Order strattera overnight Sertraline appears to have an even lower risk than some antidepressants, such as venlafaxine. Interactions. CYP2D6 inhibition. Inhibition of CYP2D6 was found to result in 2 to 10-fold higher level of a TCA. This could have an impact on other drugs reliant on CYP2D6 for metabolism. Antiplatelet drugs A list of drugs that interact with Sertraline. Both sertraline and methylthioninium chloride can increase the risk of serotonin syndrome. Some fruit juices and fruits can interact with numerous drugs, in many cases causing adverse effects. The effect was first discovered accidentally, when a test of drug interactions with alcohol used grapefruit juice to hide the taste of the ethanol. Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition. Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed. Show More Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. After one week, the dose should be increased to 50mg once daily. This dosage regimen has been shown to reduce the frequency of early treatment emergent side effects characteristic of panic disorder. Patients not responding to a 50mg dose may benefit from dose increases. Dose changes should be made in steps of 50mg at intervals of at least one week, up to a maximum of 200mg/day. Changes in dose should not be made more frequently than once per week given the 24-hour elimination half life of sertraline. Longer-term treatment may also be appropriate for prevention of recurrence of major depressive episodes (MDE). In most of the cases, the recommended dose in prevention of recurrence of MDE is the same as the one used during current episode. Sertraline drug interaction Sertraline Zoloft, Lustral, Serlain, Apo-Sentral, Asenta., Sertraline Interactions BNF content published by NICE Where can i buy tretinoin onlinePropecia 1mg side effects Medications are known to interact with sertraline. Includes tramadol, aspirin, trazodone. Sertraline Drug Interactions -. Grapefruit–drug interactions - Wikipedia. ZOLOFT® sertraline HCl Drug Interactions Pfizer Medical.. OCD, panic disorder, PTSD, PMDD-specific dosing for Zoloft sertraline, frequency-based adverse effects, comprehensive interactions. Drugs & Diseases. An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed. Medications other than those listed above may interact with this medication. Severe Interactions of sertraline include. interactions with at least 73 different drugs.